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complement activation中文是什么意思

  • 补体激活

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  • 例句与用法
  • Standard practice for testing for whole complement activation in serum by solid materials
    用固体材料测试血浆中整个活性的标准操作规程
  • Standard practice for testing for alternative pathway complement activation in serum by solid materials
    通过固体材料测试血清中替换途径互补活化性的标准实施规程
  • However , complement activation presents a potential threat to host cells , as inappropriate activation may lead to tissue damage in many diseases
    然而,对机体来说,补体也具有潜在的威胁,其经过不适宜的活化后,可以导致机体多种组织的损伤。
  • An array of regulatory proteins have been found , which inhibit the formation of central enzymes involved in early stages of the complement activation pathway . these include membrane cofactor protein ( mcp cd46 ) , decay - accelerating factor protein ( daf cd5 5 ) , complement receptor 1 ( cr1 , cd35 ) , as well as cd59 , which inhibits formation of the membrane attack complex during later stages . these regulatory factors are widely expressed and abundant on many cells , and in fluids of reproductive system
    目前发现,机体多种细胞以及生殖系统的体液中表达和分泌丰富的补体调控蛋白,包括作用于补体活化早期阶段的cd55 、 cd46 、 cd35和作用于补体活化终末阶段的cd59 ,它们分别通过抑制补体活化过程中关键的c3 、 c5转化酶和抑制形成膜攻击单位,抵抗补体对自身组织细胞的攻击。
  • We focused on the following aspects ; 1 ) we first assayed the expression of complement receptors and complement - associated molecules on distinct subsets of dendritic cells during their development in order to understand the physical basis of the sensitivity of dendritic cells to complement and its split products ; we next studied the effects of complement activation on the survival of dendritic cells during their development ; and finally examined the effects of the whole complement system , focusing on the ability of one of the split products of complement activation , c5a , and its first subcomponent - c1q , to influence chemotaxis of dendritic cells , as well as allo - t cell stimulatory activity of dc
    我们通过免疫磁珠分离了两种人dc前体,即髓系来源的单核细胞( monocytes , mo )和淋巴系来源的浆细胞样dc ( plasmaeytoiddendriticeells , pdc ) ,对这两个不同dc亚群进行体外诱导培养,使其处于不同的分化发育阶段,然后检测了其表达补体受体一cd35 ( cri ) 、 cd21 ( crz ) 、 cdilb ( cr3 ) 、 cdlle ( cr4 ) ,补体调控蛋白一cd46 、 cd55 、以及部分补体片断分子受体一c3ar 、 csar 、 clqrp的水平。
  • As an important innate immune system , and as an important arm of the humoral immune response , the complement system is immediately ready to target and eliminate virus particles , to lysis those virions that have lipoprotein membranes , or to prevent it from entering host cells , or to marker them for destruction by other branch of the immune response . at the same time , the host normal tissue are protected from damaging by complement through recognizing the regulators of complement activation ( rca ) expressed on self cells
    作为机体重要的天然免疫防御系统及特异性体液免疫应答的重要效应系统,补体系统除了具有溶解、清除病毒等致病微生物,阻止病毒进入靶细胞,调理病毒的吞噬等重要功能外,还可通过“识别”自身组织细胞表面的补体活化调节蛋白来对自身细胞加以保护,使之不受侵害。
  • Almost one - third of all proteases can be classified as serine proteases , including complement subcomponent clr / cls , mannose - associated serine proteases ( masps ) , ovochymase , spermadhesin , type ii transmembrane serine proteases ( ttsps ) etc . these proteins are involved in diverse biological processes , including developmental processes such as complement activation , ovulation , fertilization , tissue remodeling , cellular migration , cancer invasion and metastasis , intestinal digestion , embryogenesis , or organogenesis
    丝氨酸蛋白酶( serineprotease )是机体最重要的酶分子之一,约占机体蛋白酶的三分之一,我们较熟知的丝氨酸蛋白酶就包括补体组分c1r c1s 、甘露糖结合丝氨酸蛋白酶、 ovochymase 、 spermadhesin和型跨膜丝氨酸蛋白酶等,它们参与了补体活化、排卵、授精、组织重建、细胞迁移、肿瘤浸润和转移、消化、胚胎发育、器官形成等多项生理功能。
  • To answer this question , a bispecific , trifunctional antibody constructs which can not only target block virus incorporated rca , but also can induce complement activation by it ' s fc fragment were designed and constructed and iv the role of this kind of bispecific antibody in virus neutralization was studied . 1 . to test our idea , human immunodeficient virus ( hiv ) and enveloped extracellular virus ( eev ) of vaccinia virus ( vv ) were selected in our study because of their complex immune evasion stratiges , their threaten to humans , and because both these two kinds of virus can escape complement attack by incorporating host rca into their envelope
    以严重危害人类健康,且具有复杂免疫逃避机制的有包膜的hiv病毒及痘苗病毒的eev病毒为研究对象,首先对它们逃避补体攻击的现象进行了验证,探讨了宿主膜补体调节蛋白cd55 、 cd59与hiv病毒及eev病毒免疫逃避的关系,评价了病毒结合的这两种补体调节蛋白作为本研究提出的,通过消除病毒逃避补体攻击的机制来恢复病毒对补体攻击的敏感性,提高补体抗病毒效率这一抗病毒策略的靶点的可能性。
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Last modified time:Tue, 12 Aug 2025 00:29:56 GMT

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